Clinical Trials Summary

Topic Study No. Clinical Trial Protocol Investigators
Acoustic Neuroma Investigator Initiated A Multicenter Prospective Analysis of Treatment Outcomes in Patients with Large Acoustic Neuromas Receiving Subtotal Resection with Backup Stereotactic Radiation Therapy Philip V Theodosopoulos (PI)
John M Tew
All Tumors Investigator Initiated Head and Spine Tissue Bank and Registry Christopher M McPherson (PI)
Yash J Patil
John M Tew
Philip V Theodosopoulos
Ronald E Warnick
Mario Zuccarello
All Tumors (Newly Diagnosed) OBTS Ohio Brain Tumor Study (OBTS) Christopher M McPherson (PI)
Margie Gerena Lewis
Ronald E Warnick
Brain Metastasis RTOG 0614 A Randomized, Phase III, Double-Blind, Placebo-Controlled Trial of Memantine for Prevention of Cognitive Dysfunction in Patients Receiving Whole-Brain Radiotherapy Kevin P Redmond (PI)
John C Breneman
Jessica N Guarnaschelli
Olivier Rixe
Glioblastoma RTOG 0825 A Phase III Double-Blind Placebo-Controlled Trial of Conventional Concurrent Chemoradiation and Adjuvant Temozolomide Plus Bevacizumab versus Conventional Concurrent Chemoradiation and Adjuvant Temozolomide in Patients with Newly Diagnosed Glioblastoma Kevin P Redmond (PI)
John C Breneman
Margie Gerena Lewis
Jessica N Guarnaschelli
Glioblastoma NCCTG N057k Phase I/II Evaluation of Everolimus (RAD001), Radiation and Temozolomide (TMZ) Followed by Adjuvant/Temozolomide and Everolimus in Newly Diagnosed Glioblastoma Olivier Rixe (PI)
John C Breneman
Jessica N Guarnaschelli
Christopher M McPherson
Ronald E Warnick
High Grade Gliomas UCBTC-G1 3T versus 1.5T MRI approach in target definition for malignant gliomas: Is there a significant difference in tumor extent and radiation treatment volume? Jessica N Guarnaschelli (PI)
William L Barrett
John C Breneman
Christopher M McPherson
Ronald E Warnick
Low Grade Glioma CTSU E3F05 Phase III Study of Radiation Therapy with or without Temozolomide for Symptomatic or Progressive Low-Grade Gliomas Olivier Rixe (PI)
John C Breneman
Jessica N Guarnaschelli
Christopher M McPherson
Ronald E Warnick
Recurrent Glioblastoma Investigator Initiated A Phase I/II Trial for Patients with Recurrent Resectable Glioblastoma Multiforme Using Surgery with Implantable BCNU Polymer Followed by Post-operative Irinotecan and Bevacizumab Margie Gerena Lewis (PI)
Christopher M McPherson
Olivier Rixe
Ronald E Warnick
Recurrent Glioblastoma RTOG 0627 A Phase II Trial of Dasatinib in Patients with Recurrent Glioblastoma Multiforme Kevin P Redmond (PI)
Margie Gerena Lewis
Olivier Rixe